Mission & Vision

Nourish Appalachia advances accessible psychiatric and neurological treatments for underserved communities through AI-powered drug repurposing.

The Challenge

Appalachian communities face disproportionate burdens of:

  • Substance use disorders - opioid overdose rates 45% higher than national average

  • Mental health conditions - limited access to specialized psychiatric care

  • Neurodevelopmental disorders - 30% higher prevalence in rural regions

  • Chronic pain syndromes - affecting 1 in 3 adults in Appalachia

Traditional drug development takes 10-15 years and billions of dollars. Communities in crisis can't wait.

Our Solution

We use artificial intelligence to identify new uses for existing FDA-approved drugs, focusing on conditions that disproportionately affect Appalachian populations. By repurposing drugs with established safety profiles, we can:

  • Accelerate access to new treatments (2-3 years vs 10-15)

  • Reduce costs by 90% compared to traditional development

  • Focus on neglected conditions affecting rural communities

  • Empower local providers with evidence-based off-label options

Our Impact

  • Free AI analyses provided to 25+ researchers

  • 3 promising candidates identified for opioid use disorder

  • Partnerships with regional health systems

  • Open-access research advancing the field

Learn About Our Approach